The newest test dimensions of these analyses wasn’t https://datingranking.net/es/citas-gay/ set a beneficial priori, and only this new readily available research out-of for every analysis were utilized.
Patient features and you may variation with age
Dining table step 1 identifies this new baseline functions of your 6442 people examined (A lot more file 1: Dining table S1 provides these types of data for each analysis). Total, quite less than one-1 / 2 of the newest customers was in fact girls, although this ratio improved which have increasing ages. Brand new mean (SD) age of customers are 63.dos (ten.9) age, in addition to their anthropometric methods showed that 46.5% was within the a number of obesity [complete mean (SD) BMI: 30.step three (5.2) kg/m 2 ], mainly of your central type of (indicate sides circumference, all: 101.8 cm; women: 99.5 cm, men: 103.eight cm). The brand new suggest (SD) lifetime of T2D was seven.cuatro (six.7) many years, and most 90% away from patients had been researching oral antidiabetes medication; others are researching life change advice only. Indicate FBG and, such as for example, suggest HbA1c was indeed more than ancient low-custom required aim (suggest FBG: 9.0 mmol/L; mean HbA1c: 7.4%). Except that HDL-C, SBP, and DBP, imply philosophy of your kept ancient cardio exposure affairs (LDL-C and triglycerides) were over its demanded thresholds. This type of thresholds are summarized during the Shape step 1.
Vintage cardio exposure items or other patient attributes stratified by years, Bmi, and you may HbA1c selections. Philosophy was means and you will 95% rely on periods, computed in the conveyed strata of your situated parameters (age, Body mass index, and you may HbA1c). The brand new straight dotted lines in a few maps show address philosophy required of the Western All forms of diabetes Connection . Celebs = age; Triangles = BMI; Groups = HbA1c. Abbreviations: Body mass index, bmi; DBP, diastolic hypertension; FBG, smooth blood sugar; HbA1c, glycosylated hemoglobin; HDL, high-thickness lipoprotein; LDL, low-occurrence lipoprotein; SBP, systolic blood pressure levels; T2D, type 2 diabetes.
A greater proportion of men than women was in the overweight range (BMI 25 to <30 kg/m 2 ), while women were more frequently in the obese range (BMI ?30 kg/m 2 ), in particular BMI 35 to <40 kg/m 2 . Smoking was more common among men than women (Table 1).There was an inverse relationship between age group and BMI, HbA1c, triglyceride, and DBP levels (Figure 1 stars: charts 2, 5, 8, and 10, respectively). Conversely, as age increased, the duration of T2D also increased, as did HDL-C and SBP levels (Figure 1 stars: charts 4, 6, and 9, respectively).
Bmi and you will cardiovascular chance items
Triglyceride, SBP, and DBP levels were directly correlated with BMI strata (Figure 1 triangles: charts 8–10, respectively). Conversely, as BMI increased, HDL-C levels decreased (Figure 1 triangles: chart 6); LDL-C levels did not show strong trends with BMI in either direction (Figure 1 triangles: chart 7). The generalized logit analysis confirmed positive associations between increasing BMI strata and SBP, DBP, and triglyceride levels as significant (P < .05 for all). It also indicated an inverse association between increasing BMI strata and HDL-C levels (P < .001) and a weaker inverse association between increasing BMI strata and LDL-C levels (P < .05).
There was an inverse relationship between BMI strata and both age and duration of T2D (Figure 1 triangles: charts 1 and 4, respectively). The generalized logit analysis confirmed these associations were significant (P < .001). HbA1c did not appear to be correlated with BMI strata (Figure 1 triangles: chart 5). 001).
HbA1c and aerobic chance products
Increased values for the cardiovascular risk factors LDL-C, triglycerides, SBP, and DBP, and decreased levels of HDL-C were related to higher HbA1c strata (Figure 1 circles: charts 7–10 and 6, respectively). In the generalized logit analysis, lower HDL-C (P < .001) and higher TC levels (P < .001) were associated with higher HbA1c strata. BMI and waist circumference did not show an association with HbA1c (Figure 1 circles: charts 2 and 3, respectively).
